Tetracycline Loaded CollagenHydroxyapatite Composite Materials for Biomedical Applications
Joint Authors
Albu, Mădălina
Sinescu, Cosmin
Negrutiu, Meda Lavinia
Rusu, Laura Cristina
Nedelcu, Ioan Avram
Sonmez, Maria
Voicu, Georgeta
Radulescu, Marius
Ficai, Denisa
Ficai, Anton
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The paper describes the preparation, characterisation, and testing of tetracycline loaded collagen-carboxymethylcellulose/hydroxyapatite ternary composite materials.
The synthesis of this drug delivery system consists in two steps: the first step is the mineralization of collagen-carboxymethylcellulose gel while the second step corresponds to the loading of the ternary composite material with tetracycline.
The obtained DDS is characterised by physicochemical, morphological, and release behaviour by using FTIR spectroscopy and microscopy, scanning electron microscopy, and UV-VIS spectroscopy.
Based on the release study, it can be assumed that tetracycline is released in a prolonged way, assuring at least 6 days of antiseptic properties.
American Psychological Association (APA)
Rusu, Laura Cristina& Nedelcu, Ioan Avram& Albu, Mădălina& Sonmez, Maria& Voicu, Georgeta& Radulescu, Marius…[et al.]. 2015. Tetracycline Loaded CollagenHydroxyapatite Composite Materials for Biomedical Applications. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1068945
Modern Language Association (MLA)
Rusu, Laura Cristina…[et al.]. Tetracycline Loaded CollagenHydroxyapatite Composite Materials for Biomedical Applications. Journal of Nanomaterials No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1068945
American Medical Association (AMA)
Rusu, Laura Cristina& Nedelcu, Ioan Avram& Albu, Mădălina& Sonmez, Maria& Voicu, Georgeta& Radulescu, Marius…[et al.]. Tetracycline Loaded CollagenHydroxyapatite Composite Materials for Biomedical Applications. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1068945
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068945