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The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation
Joint Authors
Liu, Wenyong
Qiao, Huiting
Wang, Daifa
Wang, Yu
Gu, Hongyu
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The inhaled nanoparticles have attracted more and more attention, since they are more easily to enter the deep part of respiratory system.
Some nanoparticles were reported to cause pulmonary inflammation.
The toxicity of nanoparticles depends not only on its chemical component but also on the quantity and position of the deposition.
The deposition of nanoparticles is not uniform and is influenced by airflow transport.
The high deposition mainly occurs at the carinal ridges and the inside walls around the carinal ridges.
Many factors could affect the transport and deposition of nanoparticles, such as particle size, flow rate, structure of airway, pulmonary function, and age.
In this review, we discussed the methods and technique involved in particle transport and deposition studies.
The features of particles deposition could be observed in clinic experiments and animal experiments.
The mechanism of transport could be studied by numerical simulation.
Numerical model and experiment study supplement each other.
Some techniques such as medical imaging may support the study of nanoparticles transport and deposition.
The knowledge of particles transport and deposition may be helpful both to defend the toxicity of inhaled particles and to direct inhaled drug delivery.
American Psychological Association (APA)
Qiao, Huiting& Liu, Wenyong& Gu, Hongyu& Wang, Daifa& Wang, Yu. 2015. The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1068981
Modern Language Association (MLA)
Qiao, Huiting…[et al.]. The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation. Journal of Nanomaterials No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1068981
American Medical Association (AMA)
Qiao, Huiting& Liu, Wenyong& Gu, Hongyu& Wang, Daifa& Wang, Yu. The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1068981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068981