The Effect of Charge at the Surface of Silver Nanoparticles on Antimicrobial Activity against Gram-Positive and Gram-Negative Bacteria: A Preliminary Study
Joint Authors
Gholami, Ahmad
Abbaszadegan, Abbas
Ghahramani, Yasamin
Dorostkar, Samira
Nabavizadeh, Mohammadreza
Sharghi, Hashem
Hemmateenejad, Bahram
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The bactericidal efficiency of various positively and negatively charged silver nanoparticles has been extensively evaluated in literature, but there is no report on efficacy of neutrally charged silver nanoparticles.
The goal of this study is to evaluate the role of electrical charge at the surface of silver nanoparticles on antibacterial activity against a panel of microorganisms.
Three different silver nanoparticles were synthesized by different methods, providing three different electrical surface charges (positive, neutral, and negative).
The antibacterial activity of these nanoparticles was tested against gram-positive (i.e., Staphylococcus aureus, Streptococcus mutans, and Streptococcus pyogenes) and gram-negative (i.e., Escherichia coli and Proteus vulgaris) bacteria.
Well diffusion and micro-dilution tests were used to evaluate the bactericidal activity of the nanoparticles.
According to the obtained results, the positively-charged silver nanoparticles showed the highest bactericidal activity against all microorganisms tested.
The negatively charged silver nanoparticles had the least and the neutral nanoparticles had intermediate antibacterial activity.
The most resistant bacteria were Proteus vulgaris.
We found that the surface charge of the silver nanoparticles was a significant factor affecting bactericidal activity on these surfaces.
Although the positively charged nanoparticles showed the highest level of effectiveness against the organisms tested, the neutrally charged particles were also potent against most bacterial species.
American Psychological Association (APA)
Abbaszadegan, Abbas& Ghahramani, Yasamin& Gholami, Ahmad& Hemmateenejad, Bahram& Dorostkar, Samira& Nabavizadeh, Mohammadreza…[et al.]. 2015. The Effect of Charge at the Surface of Silver Nanoparticles on Antimicrobial Activity against Gram-Positive and Gram-Negative Bacteria: A Preliminary Study. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069264
Modern Language Association (MLA)
Abbaszadegan, Abbas…[et al.]. The Effect of Charge at the Surface of Silver Nanoparticles on Antimicrobial Activity against Gram-Positive and Gram-Negative Bacteria: A Preliminary Study. Journal of Nanomaterials No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069264
American Medical Association (AMA)
Abbaszadegan, Abbas& Ghahramani, Yasamin& Gholami, Ahmad& Hemmateenejad, Bahram& Dorostkar, Samira& Nabavizadeh, Mohammadreza…[et al.]. The Effect of Charge at the Surface of Silver Nanoparticles on Antimicrobial Activity against Gram-Positive and Gram-Negative Bacteria: A Preliminary Study. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069264
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069264