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Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε-caprolactone)Chitosan Nanofibers
Joint Authors
Sultana, Naznin
Roozbahani, Fatemeh
Naghizadeh, Farnaz
Almasi, D.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Poly(ε-caprolactone)/chitosan (PCL/chitosan) blend nanofibers with different ratios of chitosan were electrospun from a formic acid/acetic acid (FA/AA) solvent system.
Bovine serum albumin (BSA) was used as a model protein to incorporate biochemical cues into the nanofibrous scaffolds.
The morphological characteristics of PCL/chitosan and PCL/chitosan/BSA Nanofibers were investigated by scanning electron microscopy (SEM).
Fourier transform infrared spectroscopy (FTIR) was used to detect the presence of polymeric ingredients and BSA in the Nanofibers.
The effects of the polymer blend ratio and BSA concentration on the morphological characteristics and consequently on the BSA release pattern were evaluated.
The average fiber diameter and pore size were greater in Nanofibers containing BSA.
The chitosan ratio played a significant role in the BSA release profile from the PCL/chitosan/BSA blend.
Nanofibrous scaffolds with higher chitosan ratios exhibited less intense bursts in the BSA release profile.
American Psychological Association (APA)
Roozbahani, Fatemeh& Sultana, Naznin& Almasi, D.& Naghizadeh, Farnaz. 2015. Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε-caprolactone)Chitosan Nanofibers. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1069284
Modern Language Association (MLA)
Roozbahani, Fatemeh…[et al.]. Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε-caprolactone)Chitosan Nanofibers. Journal of Nanomaterials No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1069284
American Medical Association (AMA)
Roozbahani, Fatemeh& Sultana, Naznin& Almasi, D.& Naghizadeh, Farnaz. Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε-caprolactone)Chitosan Nanofibers. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1069284
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069284