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Antibacterial and Antibiofilm Activities of the Photothermal Therapy Using Gold Nanorods against Seven Different Bacterial Strains
Joint Authors
Martínez-Gutiérrez, F.
Zavala Alonso, N. V.
Niño Martínez, N.
Zaragoza-Magaña, Valentin
Cabral-Romero, Claudio
Castillo-Martínez, Juan Carlos
Patiño-Marín, Nuria
Martínez-Castañón, G.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The objective of this work was to determine the bactericidal and antibiofilm activities of gold nanorods (AuNRs) using plasmonic photothermal therapy (PPTT) against oral microorganisms.
AuNRs were synthesized by the seed and growth solution method and the gold nanoclusters were characterized with a size of 33.2 nm ± 2.23 length and 7.33 nm ± 1.60 width.
The efficacy of PPTT related to its temperature was done reaching 67°C.
Minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC) of AuNRs and AuNRs PPTT were determined against Enterococcus faecalis, Staphylococcus aureus, Streptococcus mutans, Streptococcus sobrinus, Streptococcus oralis, Streptococcus salivarius, and Escherichia coli growth.
The antibiofilm activity of AuNRs was explored by fluorescence microscopy.
After experimental analyses, AuNRs PPTT shows better results in MICs and MBCs, when it was compared with AuNRs alone.
The laser employed to activate the AuNRs had no antibacterial effect against oral microbes.
The MICs and MBCs values were higher for S.
aureus and E.
coli and lower against S.
oralis.
Surprisingly, the AuNRs alone presented a high antibiofilm activity, inhibiting the biofilm formation of S.
mutans.
Altogether, these results strongly suggest that AuNRs could be an interesting option to control oral biofilms.
American Psychological Association (APA)
Castillo-Martínez, Juan Carlos& Martínez-Castañón, G.& Martínez-Gutiérrez, F.& Zavala Alonso, N. V.& Patiño-Marín, Nuria& Niño Martínez, N.…[et al.]. 2015. Antibacterial and Antibiofilm Activities of the Photothermal Therapy Using Gold Nanorods against Seven Different Bacterial Strains. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069302
Modern Language Association (MLA)
Castillo-Martínez, Juan Carlos…[et al.]. Antibacterial and Antibiofilm Activities of the Photothermal Therapy Using Gold Nanorods against Seven Different Bacterial Strains. Journal of Nanomaterials No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1069302
American Medical Association (AMA)
Castillo-Martínez, Juan Carlos& Martínez-Castañón, G.& Martínez-Gutiérrez, F.& Zavala Alonso, N. V.& Patiño-Marín, Nuria& Niño Martínez, N.…[et al.]. Antibacterial and Antibiofilm Activities of the Photothermal Therapy Using Gold Nanorods against Seven Different Bacterial Strains. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069302
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069302