Antibacterial Activity and Cytocompatibility of PLGACuO Hybrid Nanofiber Scaffolds Prepared by Electrospinning
Joint Authors
Haider, Adnan
Kwak, Sanghwa
Kang, Inn-Kyu
Gupta, Kailash Chandra
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-29
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The PLGA/CuO hybrid nanofibers scaffolds were prepared via electrospinning technique.
The presence of CuO in the PLGA scaffolds was confirmed by transmission electron microscope (TEM) and X-ray photoelectron spectroscopy (XPS).
The scaffolds were subjected to various antibacterial and cytobiocompatibility tests.
The results not only showed excellent adhesion, proliferation, and viability (live/dead staining) for fibroblastic cells but also revealed that PLGA/CuO hybrid nanofiber scaffolds inhibited both Gram-positive and Gram-negative bacterial growth.
The mechanism of the antibacterial activity was concluded to be based on the CuO nanoparticles and Cu++ ions release.
It is, therefore, evaluated that PLGA/CuO hybrid nanofiber scaffolds can be a useful candidate for wound dressing.
American Psychological Association (APA)
Haider, Adnan& Kwak, Sanghwa& Gupta, Kailash Chandra& Kang, Inn-Kyu. 2015. Antibacterial Activity and Cytocompatibility of PLGACuO Hybrid Nanofiber Scaffolds Prepared by Electrospinning. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069358
Modern Language Association (MLA)
Haider, Adnan…[et al.]. Antibacterial Activity and Cytocompatibility of PLGACuO Hybrid Nanofiber Scaffolds Prepared by Electrospinning. Journal of Nanomaterials No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1069358
American Medical Association (AMA)
Haider, Adnan& Kwak, Sanghwa& Gupta, Kailash Chandra& Kang, Inn-Kyu. Antibacterial Activity and Cytocompatibility of PLGACuO Hybrid Nanofiber Scaffolds Prepared by Electrospinning. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069358
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069358