Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties
Joint Authors
Sultana, Naznin
Lim, Mim Mim
Chong, Lor Huai
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Nanofibrous scaffolds were fabricated through blending of a synthetic polymer, polycaprolactone (PCL), and a natural polymer, gelatin (GE), using an electrospinning technique.
Processing and solution parameters were optimized to determine the suitable properties of PCL/GE-based nanofibers.
Several characterizations were conducted to determine surface morphology by scanning electron microscopy (SEM), wettability using water contact angle measurement, and chemical bonding analysis using attenuated total reflectance (ATR) of PCL/GE-based nanofibers.
Experimental results showed that 14% (w/v) PCL/GE with a flow rate of 0.5 mL/h and 18 kV demonstrated suitable properties.
This nanofiber was then further investigated for its in vitro degradation, drug loading (using a model drug, tetracycline hydrochloride), and antibacterial testing (using zone inhibition method).
American Psychological Association (APA)
Chong, Lor Huai& Lim, Mim Mim& Sultana, Naznin. 2015. Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069484
Modern Language Association (MLA)
Chong, Lor Huai…[et al.]. Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties. Journal of Nanomaterials No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069484
American Medical Association (AMA)
Chong, Lor Huai& Lim, Mim Mim& Sultana, Naznin. Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069484
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069484