Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties

Joint Authors

Sultana, Naznin
Lim, Mim Mim
Chong, Lor Huai

Source

Journal of Nanomaterials

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-08-03

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Chemistry
Civil Engineering

Abstract EN

Nanofibrous scaffolds were fabricated through blending of a synthetic polymer, polycaprolactone (PCL), and a natural polymer, gelatin (GE), using an electrospinning technique.

Processing and solution parameters were optimized to determine the suitable properties of PCL/GE-based nanofibers.

Several characterizations were conducted to determine surface morphology by scanning electron microscopy (SEM), wettability using water contact angle measurement, and chemical bonding analysis using attenuated total reflectance (ATR) of PCL/GE-based nanofibers.

Experimental results showed that 14% (w/v) PCL/GE with a flow rate of 0.5 mL/h and 18 kV demonstrated suitable properties.

This nanofiber was then further investigated for its in vitro degradation, drug loading (using a model drug, tetracycline hydrochloride), and antibacterial testing (using zone inhibition method).

American Psychological Association (APA)

Chong, Lor Huai& Lim, Mim Mim& Sultana, Naznin. 2015. Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069484

Modern Language Association (MLA)

Chong, Lor Huai…[et al.]. Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties. Journal of Nanomaterials No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069484

American Medical Association (AMA)

Chong, Lor Huai& Lim, Mim Mim& Sultana, Naznin. Fabrication and Evaluation of PolycaprolactoneGelatin-Based Electrospun Nanofibers with Antibacterial Properties. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069484

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1069484