Pulmonary Venous Obstruction in Cancer Patients
Joint Authors
Wen, Ming-Shien
Liaw, Chuang-Chi
Chang, Hung
Yang, Tsai-Sheng
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
We study the clinical significance and management of pulmonary venous obstruction in cancer patients.
Methods.
We conducted a prospective cohort study to characterize the syndrome that we term “pulmonary vein obstruction syndrome” (PVOS) between January 2005 and March 2014.
The criteria for inclusion were (1) episodes of shortness of breath; (2) chest X-ray showing abnormal pulmonary hilum shadow with or without presence of pulmonary edema and/or pleural effusion; (3) CT scan demonstrating pulmonary vein thrombosis/tumor with or without tumor around the vein.
Results.
Two hundred and twenty-two patients developed PVOS.
Shortness of breath was the main symptom, which was aggravated by chemotherapy in 28 (13%), and medical/surgical procedures in 21 (9%) and showed diurnal change in intensity in 32 (14%).
Chest X-rays all revealed abnormal pulmonary hilum shadows and presence of pulmonary edema in 194 (87%) and pleural effusion in 192 (86%).
CT scans all showed pulmonary vein thrombosis/tumor (100%) and surrounding the pulmonary veins by tumor lesions in 140 patients (63%).
PVOS was treated with low molecular weight heparin in combination with dexamethasone, and 66% of patients got clinical/image improvement.
Conclusion.
Physicians should be alert to PVOS when shortness of breath occurs and chest X-ray reveals abnormal pulmonary hilum shadows.
American Psychological Association (APA)
Liaw, Chuang-Chi& Chang, Hung& Yang, Tsai-Sheng& Wen, Ming-Shien. 2015. Pulmonary Venous Obstruction in Cancer Patients. Journal of Oncology،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069563
Modern Language Association (MLA)
Liaw, Chuang-Chi…[et al.]. Pulmonary Venous Obstruction in Cancer Patients. Journal of Oncology No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1069563
American Medical Association (AMA)
Liaw, Chuang-Chi& Chang, Hung& Yang, Tsai-Sheng& Wen, Ming-Shien. Pulmonary Venous Obstruction in Cancer Patients. Journal of Oncology. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069563
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069563