Hematopoietic Stem-Cell Transplantation in the Developing World: Experience from a Center in Western India
Joint Authors
Shah, Chirag A.
Karanwal, Arun
Desai, Maharshi
Pandya, Munjal
Shah, Ravish
Shah, Rutvij
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We describe our experience of first 50 consecutive hematopoietic stem-cell transplants (HSCT) done between 2007 and 2012 at the Apollo Hospital, Gandhinagar, 35 autologous HSCT and 15 allogeneic HSCT.
Indications for autologous transplant were multiple myeloma, non-Hodgkin lymphoma, Hodgkin lymphoma, and acute myeloid leukemia, and indications for allogeneic transplants were thalassemia major, aplastic anaemia, chronic myeloid leukemia, and acute lymphoblastic and myeloid leukaemia.
The median age of autologous and allogeneic patient’s cohort was 50 years and 21 years, respectively.
Median follow-up period for all patients was 39 months.
Major early complications were infections, mucositis, acute graft versus host disease, and venoocclusive disease.
All of our allogeneic and autologous transplant patients survived during the first month of transplant.
Transplant related mortality (TRM) was 20% (N = 3) in our allogeneic and 3% (N = 1) in autologous patients.
Causes of these deaths were disease relapse, sepsis, hemorrhagic complications, and GVHD.
46% of our autologous and 47% of our allogeneic patients are in complete remission phase after a median follow-up of 39 months.
34% of our autologous patients and 13% of our allogeneic patients had disease relapse.
Overall survival rate in our autologous and allogeneic patients is 65.7% and 57.1%, respectively.
Our results are comparable to many national and international published reports.
American Psychological Association (APA)
Shah, Chirag A.& Karanwal, Arun& Desai, Maharshi& Pandya, Munjal& Shah, Ravish& Shah, Rutvij. 2015. Hematopoietic Stem-Cell Transplantation in the Developing World: Experience from a Center in Western India. Journal of Oncology،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1069584
Modern Language Association (MLA)
Shah, Chirag A.…[et al.]. Hematopoietic Stem-Cell Transplantation in the Developing World: Experience from a Center in Western India. Journal of Oncology No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1069584
American Medical Association (AMA)
Shah, Chirag A.& Karanwal, Arun& Desai, Maharshi& Pandya, Munjal& Shah, Ravish& Shah, Rutvij. Hematopoietic Stem-Cell Transplantation in the Developing World: Experience from a Center in Western India. Journal of Oncology. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1069584
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069584