Role of Rebiopsy in Relapsed Non-Small Cell Lung Cancer for Directing Oncology Treatments
Author
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
Currently, few rebiopsies are performed in relapses of advanced non-small cell lung cancer.
They are not customary in clinical practice of lung cancer.
However, it is not possible to properly target treatments in cases of relapse without knowing the nature of new lesions.
Design.
This paper comprehensively summarizes the available literature about rebiopsy and broadly discusses the importance of rebiopsy in advanced non-small cell lung cancer.
Results.
Altogether 560 abstracts were used as material for further analysis.
19 articles were about clinical rebiopsy in lung cancer and were reviewed in detailed manner.
Conclusions.
This review shows that rebiopsy is feasible in non-small cell lung cancer, and success rates can be high if rebiopsy is accompanied by adequate evaluation before biopsy.
Its use may resolve the difficulties in sampling bias and detecting changes in cancer characteristics.
In cases where treatment was selected based on tissue characteristics that then change, the treatment selection process must be repeated while considering new characteristics of the tumor.
Rebiopsy may be used to predict therapeutic resistance and consequently redirect targeted therapies.
Such knowledge may resolve the difficulties in sampling bias and also in selecting preexisting clones or formulating drug-resistant ones.
Rebiopsy should be performed more often in non-small cell lung cancer.
American Psychological Association (APA)
Jekunen, Antti P.. 2015. Role of Rebiopsy in Relapsed Non-Small Cell Lung Cancer for Directing Oncology Treatments. Journal of Oncology،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1069588
Modern Language Association (MLA)
Jekunen, Antti P.. Role of Rebiopsy in Relapsed Non-Small Cell Lung Cancer for Directing Oncology Treatments. Journal of Oncology No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1069588
American Medical Association (AMA)
Jekunen, Antti P.. Role of Rebiopsy in Relapsed Non-Small Cell Lung Cancer for Directing Oncology Treatments. Journal of Oncology. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1069588
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069588