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Exercise Prevention of Cardiovascular Disease in Breast Cancer Survivors
Joint Authors
Davis, Margot K.
Kirkham, Amy A.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Thanks to increasingly effective treatment, breast cancer mortality rates have significantly declined over the past few decades.
Following the increase in life expectancy of women diagnosed with breast cancer, it has been recognized that these women are at an elevated risk for cardiovascular disease due in part to the cardiotoxic side effects of treatment.
This paper reviews evidence forthe role of exercise in prevention of cardiovascular toxicity associated with chemotherapy used in breast cancer, and in modifying cardiovascular risk factors in breast cancer survivors.
There is growing evidence indicating that the primary mechanism for this protective effect appears to be improved antioxidant capacity in the heart and vasculature and subsequent reduction of treatment-related oxidative stress in these structures.
Further clinical research is needed to determine whether exercise is a feasible and effective nonpharmacological treatment to reduce cardiovascular morbidity and mortality in breast cancer survivors, to identify the cancer therapies for which it is effective, and to determine the optimal exercise dose.
Safe and noninvasive measures that are sensitive to changes in cardiovascular function are required to answer these questions in patient populations.
Cardiac strain, endothelial function, and cardiac biomarkers are suggested outcome measures for clinical research in this field.
American Psychological Association (APA)
Kirkham, Amy A.& Davis, Margot K.. 2015. Exercise Prevention of Cardiovascular Disease in Breast Cancer Survivors. Journal of Oncology،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1069592
Modern Language Association (MLA)
Kirkham, Amy A.& Davis, Margot K.. Exercise Prevention of Cardiovascular Disease in Breast Cancer Survivors. Journal of Oncology No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1069592
American Medical Association (AMA)
Kirkham, Amy A.& Davis, Margot K.. Exercise Prevention of Cardiovascular Disease in Breast Cancer Survivors. Journal of Oncology. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1069592
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069592