The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells
Joint Authors
Sakurai, Takuya
Ishibashi, Yoshinaga
Shirato, Ken
Sakurai, Tomonobu
Ohno, Hideki
Ogasawara, Junetsu
Ishida, Hitoshi
Kizaki, Takako
Izawa, Tetsuya
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Physical exercise accelerates the mobilization of free fatty acids from white adipocytes to provide fuel for energy.
This happens in several tissues and helps to regulate a whole-body state of metabolism.
Under these conditions, the hydrolysis of triacylglycerol (TG) that is found in white adipocytes is known to be augmented via the activation of these lipolytic events, which is referred to as the “lipolytic cascade.” Indeed, evidence has shown that the lipolytic responses in white adipocytes are upregulated by continuous exercise training (ET) through the adaptive changes in molecules that constitute the lipolytic cascade.
During the past few decades, many lipolysis-related molecules have been identified.
Of note, the discovery of a new lipase, known as adipose triglyceride lipase, has redefined the existing concepts of the hormone-sensitive lipase-dependent hydrolysis of TG in white adipocytes.
This review outlines the alterations in the lipolytic molecules of white adipocytes that result from ET, which includes the molecular regulation of TG lipases through the lipolytic cascade.
American Psychological Association (APA)
Ogasawara, Junetsu& Izawa, Tetsuya& Sakurai, Tomonobu& Sakurai, Takuya& Shirato, Ken& Ishibashi, Yoshinaga…[et al.]. 2015. The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells. Journal of Obesity،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069611
Modern Language Association (MLA)
Ogasawara, Junetsu…[et al.]. The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells. Journal of Obesity No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1069611
American Medical Association (AMA)
Ogasawara, Junetsu& Izawa, Tetsuya& Sakurai, Tomonobu& Sakurai, Takuya& Shirato, Ken& Ishibashi, Yoshinaga…[et al.]. The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells. Journal of Obesity. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069611
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069611