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Analysis of the Retinal Nerve Fiber Layer in Retinitis Pigmentosa Using Optic Coherence Tomography
Joint Authors
Yıldırım, Medine Aslı
Erden, Burak
Tetikoğlu, Mehmet
Kuru, Özlem
Elçioğlu, Mustafa
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
To evaluate the peripapillary retinal nerve fiber layer (RNFL) changes in retinitis pigmentosa (RP) patients using spectral domain optic coherence tomography (Sd-OCT).
Methods.
We retrospectively examined medical records of forty-four eyes of twenty-two RP patients.
The results were also compared with those of previously reported forty-four eyes of twenty-two normal subjects (controls).
Records of average and four quadrants peripapillary RNFL thickness measurements using Sd-OCT were assessed.
Results.
In RP patients the mean RNFL thickness was 97.57 ± 3.21 μm.
The RNFL in the superior, temporal, nasal, and inferior quadrants was 119.18 ± 4.47 μm, 84.68 ± 2.31 μm, 75.09 ± 3.34 μm, and 113.88 ± 4.25 μm, respectively.
While the thinning of RNFL was predominantly observed in the inferior quadrant, the thickening was mostly noted in temporal quadrant.
The differences between mean, superior, and nasal quadrant RNFL thicknesses were not statistically significant when compared with control group.
The RP patients had thinner inferior quadrant and thicker temporal quadrant than control group (p<0.05).
Conclusion.
Sd-OCT is highly sensitive and effective instrument to detect RNFL changes in RP patients.
RNFL measurements can provide information about the progression of retinitis pigmentosa and may provide prognostic indices for future treatment modalities.
American Psychological Association (APA)
Yıldırım, Medine Aslı& Erden, Burak& Tetikoğlu, Mehmet& Kuru, Özlem& Elçioğlu, Mustafa. 2015. Analysis of the Retinal Nerve Fiber Layer in Retinitis Pigmentosa Using Optic Coherence Tomography. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069653
Modern Language Association (MLA)
Yıldırım, Medine Aslı…[et al.]. Analysis of the Retinal Nerve Fiber Layer in Retinitis Pigmentosa Using Optic Coherence Tomography. Journal of Ophthalmology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069653
American Medical Association (AMA)
Yıldırım, Medine Aslı& Erden, Burak& Tetikoğlu, Mehmet& Kuru, Özlem& Elçioğlu, Mustafa. Analysis of the Retinal Nerve Fiber Layer in Retinitis Pigmentosa Using Optic Coherence Tomography. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069653
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069653