Efficacy and Safety of Corneal Transplantation Using Corneas from Foreign Donors versus Domestic Donors: A Prospective, Randomized, Controlled Trial
Joint Authors
Chen, Yingxin
Liao, Congling
Gao, Minghong
Belin, Michael Wellington
Wang, Mingwu
Yu, Hai
Yu, Jing
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To assess the efficacy and safety of corneal transplantation using corneas from foreign donors.
Methods.
One hundred and eight patients needing therapeutic penetrating keratoplasty were randomly divided into 2 groups (54 cases/group): foreign group using foreign donor corneas and domestic group using domestic donor corneas.
Clinical outcome and incidence of postoperative complications were compared between groups.
Results.
No significant difference with respect to the therapeutic outcome and postoperative Best Corrected Visual Acuity (BCVA) and neovascularization by final follow-up was observed between the two groups.
The graft thickness in the foreign group was statistically higher than the domestic group at 1 month postoperatively, but not at 3, 6, and 12 months postoperatively.
Corneal endothelial cell density in the domestic group was statistically higher than in the foreign group at 3, 6, and 12 months postoperatively.
Corneal epithelial abnormalities in the foreign group were significantly higher than that in domestic group.
The primary graft failure, incidence of graft survival, and postoperative complications such as immunologic rejection, graft infection, and secondary glaucoma were not significantly different between the two groups.
Conclusions.
Corneal transplantations using foreign donor corneas are as effective and safe as those using domestic donor corneas.
American Psychological Association (APA)
Chen, Yingxin& Liao, Congling& Gao, Minghong& Belin, Michael Wellington& Wang, Mingwu& Yu, Hai…[et al.]. 2015. Efficacy and Safety of Corneal Transplantation Using Corneas from Foreign Donors versus Domestic Donors: A Prospective, Randomized, Controlled Trial. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069661
Modern Language Association (MLA)
Chen, Yingxin…[et al.]. Efficacy and Safety of Corneal Transplantation Using Corneas from Foreign Donors versus Domestic Donors: A Prospective, Randomized, Controlled Trial. Journal of Ophthalmology No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1069661
American Medical Association (AMA)
Chen, Yingxin& Liao, Congling& Gao, Minghong& Belin, Michael Wellington& Wang, Mingwu& Yu, Hai…[et al.]. Efficacy and Safety of Corneal Transplantation Using Corneas from Foreign Donors versus Domestic Donors: A Prospective, Randomized, Controlled Trial. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069661
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069661