Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis
Joint Authors
Huang, Jinhai
Bao, Fangjun
Wang, Qinmei
Wen, Daizong
Chen, Hao
Calossi, Antonio
Chen, Haisi
Li, Xuexi
Savini, G.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-11
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
To evaluate the efficacy and acceptability of orthokeratology for slowing myopic progression in children with a well conducted evidence-based analysis.
Design.
Meta-analysis.
Participants.
Children from previously reported comparative studies were treated by orthokeratology versus control.
Methods.
A systematic literature retrieval was conducted in MEDLINE, EMBASE, Cochrane Library, World Health Organization International Clinical Trials Registry Platform, and ClinicalTrials.gov.
The included studies were subjected to meta-analysis using Stata version 10.1.
Main Outcome Measures.
Axial length change (efficacy) and dropout rates (acceptability) during 2-year follow-up.
Results.
Eight studies involving 769 subjects were included.
At 2-year follow-up, a statistically significant difference was observed in axial length change between the orthokeratology and control groups, with a weighted mean difference (WMD) of −0.25 mm (95% CI, −0.30 to −0.21).
The pooled myopic control rate declined with time, with 55, 51, 51, and 41% obtained after 6, 12, 18, and 24 months of treatment, respectively.
No statistically significant difference was obtained for dropout rates between the orthokeratology and control groups at 2-year follow-up (OR, 0.79; 95% CI, 0.52 to 1.22).
Conclusions.
Orthokeratology is effective and acceptable for slowing myopic progression in children with careful education and monitoring.
American Psychological Association (APA)
Wen, Daizong& Huang, Jinhai& Chen, Hao& Bao, Fangjun& Savini, G.& Calossi, Antonio…[et al.]. 2015. Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1069708
Modern Language Association (MLA)
Wen, Daizong…[et al.]. Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis. Journal of Ophthalmology No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1069708
American Medical Association (AMA)
Wen, Daizong& Huang, Jinhai& Chen, Hao& Bao, Fangjun& Savini, G.& Calossi, Antonio…[et al.]. Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1069708
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069708