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The Vitreomacular Interface in Diabetic Retinopathy
Joint Authors
Christoforidis, John Byron
Agarwal, Daniel
Gelman, Rachel
Prospero Ponce, Claudia
Stevenson, William
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Diabetic retinopathy (DR) is a leading health concern and a major cause of blindness.
DR can be complicated by scar tissue formation, macular edema, and tractional retinal detachment.
Optical coherence tomography has found that patients with DR often have diffuse retinal thickening, cystoid macular edema, posterior hyaloid traction, and tractional retinal detachment.
Newer imaging techniques can even detect fine tangential folds and serous macular detachment.
The interplay of the vitreous and the retina in the progression of DR involves multiple chemokine and other regulatory factors including VEGF.
Understanding the cells infiltrating pathologic membranes at the vitreomacular interface has opened up the possibility of new targets for pharmacotherapy.
Vitrectomies for DR remain a vital tool to help relieve tension on the macula by removing membranes, improving edema absorption, and eliminating the scaffold for new membrane formation.
Newer treatments such as triamcinolone acetonide and VEGF inhibitors have become essential as a rapid way to control DR at the vitreomacular interface, improve macular edema, and reduce retinal neovascularization.
These treatments alone, and in conjunction with PRP, help to prevent worsening of the VMI in patients with DR.
American Psychological Association (APA)
Agarwal, Daniel& Gelman, Rachel& Prospero Ponce, Claudia& Stevenson, William& Christoforidis, John Byron. 2015. The Vitreomacular Interface in Diabetic Retinopathy. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069721
Modern Language Association (MLA)
Agarwal, Daniel…[et al.]. The Vitreomacular Interface in Diabetic Retinopathy. Journal of Ophthalmology No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1069721
American Medical Association (AMA)
Agarwal, Daniel& Gelman, Rachel& Prospero Ponce, Claudia& Stevenson, William& Christoforidis, John Byron. The Vitreomacular Interface in Diabetic Retinopathy. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069721
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069721