Human Serum Eye Drops in Eye Alterations: An Insight and a Critical Analysis
Joint Authors
Lanza, Michele
De Pascale, Maria Rosaria
Sommese, Linda
Napoli, Claudio
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-04
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Human serum contains a physiological plethora of bioactive elements naturally released by activated platelets which might have a significant effect on the regeneration of corneal layers by stimulating the cell growth.
This mechanism supported the use of human serum eye drops in some ocular diseases associated with dystrophic changes and alterations of the tear film, such as persistent corneal epithelial defects and dry eye syndrome.
We focused our effort on potential benefits and limitations of the use of human serum eye drops when conventional therapies failed.
We reviewed the recent literature by reporting published studies from 2010 to 2014.
Despite the limited evaluated study populations, most of the clinical studies have confirmed that serum eye drop therapy is effective in corneal healing by reducing ocular symptom, particularly during the short-term follow-up.
In addition, three recent published studies have shown the efficacy of the serum eye drop therapy in comparison to traditional ones in intractable patients.
Besides, reported ongoing clinical studies confirmed the open debate regarding the use of biologic tools for cornea regeneration.
Results from these studies might open novel challenges and perspectives in the therapy of such refractory patients.
American Psychological Association (APA)
De Pascale, Maria Rosaria& Lanza, Michele& Sommese, Linda& Napoli, Claudio. 2015. Human Serum Eye Drops in Eye Alterations: An Insight and a Critical Analysis. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1069722
Modern Language Association (MLA)
De Pascale, Maria Rosaria…[et al.]. Human Serum Eye Drops in Eye Alterations: An Insight and a Critical Analysis. Journal of Ophthalmology No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1069722
American Medical Association (AMA)
De Pascale, Maria Rosaria& Lanza, Michele& Sommese, Linda& Napoli, Claudio. Human Serum Eye Drops in Eye Alterations: An Insight and a Critical Analysis. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1069722
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069722