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Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma
Joint Authors
Moon, Chan Hee
Han, Jungwoo
Ohn, Young-Hoon
Park, Tae Kwann
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To investigate the local relationship between quantified global-flash multifocal electroretinogram (mfERG) optic nerve head component (ONHC) and visual field defects in patients with glaucoma.
Methods.
Thirty-nine patients with glaucoma and 30 normal controls were enrolled.
The ONHC amplitude was measured from the baseline to the peak of the second positive deflection of the induced component.
The ONHC amplitude was normalized by dividing ONHC amplitude by the average of seven largest ONHC amplitudes.
The ONHC amplitude ratio map and ONHC deficiency map were constructed.
The local relationship between the ONHC measurements and visual field defects was evaluated by calculating the overlap between the ONHC deficiency maps and visual field defect plots.
Results.
The mean ONHC amplitude measurements of patients with glaucoma (6.01±1.91 nV/deg2) were significantly lower than those of the normal controls (10.29±0.94 nV/deg2) (P<0.001).
The average overlap between the ONHC deficiency map and visual field defect plot was 71.4%.
The highest overlap (75.0%) was between the ONHC ratios less than 0.5 and the total deviations less than 5%.
Conclusions.
The ONHC amplitude was reduced in patients with glaucoma compared to that in normal controls.
Loss of the ONHC amplitude from the global-flash mfERG showed a high local agreement with visual field defects in patients with glaucoma.
American Psychological Association (APA)
Moon, Chan Hee& Han, Jungwoo& Ohn, Young-Hoon& Park, Tae Kwann. 2015. Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069723
Modern Language Association (MLA)
Moon, Chan Hee…[et al.]. Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma. Journal of Ophthalmology No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069723
American Medical Association (AMA)
Moon, Chan Hee& Han, Jungwoo& Ohn, Young-Hoon& Park, Tae Kwann. Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069723
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069723