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The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa
Joint Authors
Perri, Paolo
Bonifazzi, Claudio
Sorrentino, Francesco S.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Retinitis pigmentosa is a clinical and genetic group of inherited retinal disorders characterized by alterations of photoreceptors and retinal pigment epithelium leading to a progressive concentric visual field restriction, which may bring about severe central vision impairment.
Haemodynamic studies in patients with retinitis pigmentosa have demonstrated ocular blood flow abnormalities both in retina-choroidal and in retroocular vascular system.
Moreover, several investigations have studied the augmentation of endothelin-1 plasma levels systemically in the body and locally in the eye.
This might account for vasoconstriction and ischemia, typical in vascular dysregulation syndrome, which can be considered an important factor of reduction of the ocular blood flow in subjects affected by retinitis pigmentosa.
American Psychological Association (APA)
Sorrentino, Francesco S.& Bonifazzi, Claudio& Perri, Paolo. 2015. The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069727
Modern Language Association (MLA)
Sorrentino, Francesco S.…[et al.]. The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa. Journal of Ophthalmology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1069727
American Medical Association (AMA)
Sorrentino, Francesco S.& Bonifazzi, Claudio& Perri, Paolo. The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069727
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069727