Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?
Joint Authors
Hu, Dan-Ning
Jordan, Adrienne
Xue, Chunyan
Rosen, Richard
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Zeaxanthin and lutein are two carotenoid pigments that concentrated in the retina, especially in the macula.
The effects of lutein and zeaxanthin on the prevention and treatment of various eye diseases, including age-related macular degeneration, diabetic retinopathy and cataract, ischemic/hypoxia induced retinopathy, light damage of the retina, retinitis pigmentosa, retinal detachment, and uveitis, have been studied in different experimental animal models.
In these animal models, lutein and zeaxanthin have been reported to have beneficial effects in protecting ocular tissues and cells (especially the retinal neurons) against damage caused by different etiological factors.
The mechanisms responsible for these effects of lutein and zeaxanthin include prevention of phototoxic damage by absorption of blue light, reduction of oxidative stress through antioxidant activity and free radical scavenging, and their anti-inflammatory and antiangiogenic properties.
The results of these experimental animal studies may provide new preventive and therapeutic procedures for clinical management of various vision-threatening diseases.
American Psychological Association (APA)
Xue, Chunyan& Rosen, Richard& Jordan, Adrienne& Hu, Dan-Ning. 2015. Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1069763
Modern Language Association (MLA)
Xue, Chunyan…[et al.]. Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?. Journal of Ophthalmology No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1069763
American Medical Association (AMA)
Xue, Chunyan& Rosen, Richard& Jordan, Adrienne& Hu, Dan-Ning. Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1069763
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069763