Repeatability of Perimacular Ganglion Cell Complex Analysis with Spectral-Domain Optical Coherence Tomography
Joint Authors
Ikram, Mohammad Kamran
Ng, Dorothy S. K.
Gupta, Preeti
Tham, Yih Chung
Peck, Chye Fong
Wong, Tien Yin
Cheung, Carol Y.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To assess the repeatability of spectral-domain optical coherence tomography to measure macular and perimacular ganglion cell complex thicknesses and compare retinal ganglion cell parameters between algorithms.
Methods.
Ninety-two nonglaucomatous eyes from 92 participants underwent macular and perimacular ganglion cell complex thickness measurement using OCT-HS100 Glaucoma 3D algorithm and these measurements were repeated for 34 subjects.
All subjects also had macular ganglion cell-inner plexiform layer thickness measured by Cirrus HD-OCT Ganglion Cell Analysis algorithm.
Intraclass correlation coefficient and Pearson’s correlation analyses were performed.
Results.
Subfields of both macular and perimacular ganglion cell complex thicknesses had high intraclass correlation coefficient values between 0.979 (95% confidence interval [CI]: 0.958–0.989) and 0.981 (95% CI: 0.963, 0.991) and between 0.70 (95% CI: 0.481–0.838) and 0.987 (95% CI: 0.956–0.989), respectively.
The overall average ganglion cell complex and macular average ganglion cell-inner plexiform layer thicknesses were strongly correlated (r=0.83, P<0.001).
Conclusions.
The assessment of macular and perimacular retinal ganglion cell parameters by OCT-HS100 Glaucoma 3D algorithm is highly repeatable, and strongly correlates to retinal ganglion cell parameters assessed by Ganglion Cell Analysis algorithm.
A comprehensive evaluation of retinal ganglion cells may be possible with OCT-HS100.
American Psychological Association (APA)
Ng, Dorothy S. K.& Gupta, Preeti& Tham, Yih Chung& Peck, Chye Fong& Wong, Tien Yin& Ikram, Mohammad Kamran…[et al.]. 2015. Repeatability of Perimacular Ganglion Cell Complex Analysis with Spectral-Domain Optical Coherence Tomography. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069785
Modern Language Association (MLA)
Ng, Dorothy S. K.…[et al.]. Repeatability of Perimacular Ganglion Cell Complex Analysis with Spectral-Domain Optical Coherence Tomography. Journal of Ophthalmology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069785
American Medical Association (AMA)
Ng, Dorothy S. K.& Gupta, Preeti& Tham, Yih Chung& Peck, Chye Fong& Wong, Tien Yin& Ikram, Mohammad Kamran…[et al.]. Repeatability of Perimacular Ganglion Cell Complex Analysis with Spectral-Domain Optical Coherence Tomography. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069785
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069785