Evaluation of Idiopathic Choroidal Neovascularization with Indocyanine Green Angiography in Patients Undergoing Bevacizumab Therapy
Joint Authors
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To examine the clinical implications of change in choroidal neovascularization (CNV) size on indocyanine green (ICG) angiography in subjects with idiopathic CNV undergoing bevacizumab therapy.
Methods.
The charts of subjects with an idiopathic CNV treated by a modified PRN regimen with intravitreal bevacizumab over a 12-month period were retrospectively reviewed.
Results.
There were 34 subjects included in the analysis.
Baseline CNV sizes of less than 1.0 mm2 on ICG angiography correlated with complete CNV resolution ( P = 0.0404 ), fewer injections delivered ( P = 0.0002 ), and better Snellen visual acuity ( P = 0.0098 ) at 12 months.
Subjects that experienced a 33% or more reduction in CNV size on ICG angiography at 2 months had complete CNV resolution ( P = 0.0047 ) and fewer injections ( P < 0.0001 ) at 12 months compared to subjects that did not experience a 33% or more reduction in CNV size on ICG angiography at 2 months.
Conclusions.
Smaller baseline CNV size on ICG angiography resulted in better visual acuity and fewer injections at 12 months, and a reduction of 33% or more in CNV size after 2 months may predict a better clinical course in subjects with idiopathic CNV undergoing bevacizumab therapy.
American Psychological Association (APA)
Rush, Ryan B.& Rush, Sloan W.. 2015. Evaluation of Idiopathic Choroidal Neovascularization with Indocyanine Green Angiography in Patients Undergoing Bevacizumab Therapy. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069800
Modern Language Association (MLA)
Rush, Ryan B.& Rush, Sloan W.. Evaluation of Idiopathic Choroidal Neovascularization with Indocyanine Green Angiography in Patients Undergoing Bevacizumab Therapy. Journal of Ophthalmology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069800
American Medical Association (AMA)
Rush, Ryan B.& Rush, Sloan W.. Evaluation of Idiopathic Choroidal Neovascularization with Indocyanine Green Angiography in Patients Undergoing Bevacizumab Therapy. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069800
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069800