Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2% Fluconazole on Fungal Keratitis
Joint Authors
Shi, Weiyun
You, Xinying
Li, Jun
Li, Suxia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-07
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To evaluate effects of lamellar keratectomy and intrastromal injection of 0.2% fluconazole (LKIIF) on fungal keratitis.
Methods.
Data for 54 eyes of consecutive patients with fungal keratitis treated with LKIIF were retrospectively analyzed.
The lesions in these eyes did not heal or were aggravated after antifungal chemotherapy for 7 days.
The maximum lesion diameters were ≤5 mm and maximum depth was not more than half of full corneal thickness.
Cases were followed up for at least 90 days.
Results.
Forty-six eyes were cured (85.2%).
The wound healing times were 3–16 days and were less than 7 days in 28 cases (51.9%).
In cured eyes, uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) were both 20/250–20/20.
The UCVA improved in 38 eyes and was unchanged in seven eyes.
BCVA improved in 44 eyes and was unchanged in two eyes.
When followed up for more than 90 days, 89% (41 of 46 eyes) showed improvement in UCVA and 11% were unchanged.
Regarding BCVA, 98% improved and one eye was unchanged.
No other complications were observed except neovascularization in one eye and thinner corneas.
Conclusions.
LKIIF was quick and effective for small fungal keratitis confined to half of the corneal thickness.
American Psychological Association (APA)
You, Xinying& Li, Jun& Li, Suxia& Shi, Weiyun. 2015. Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2% Fluconazole on Fungal Keratitis. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069802
Modern Language Association (MLA)
You, Xinying…[et al.]. Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2% Fluconazole on Fungal Keratitis. Journal of Ophthalmology No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1069802
American Medical Association (AMA)
You, Xinying& Li, Jun& Li, Suxia& Shi, Weiyun. Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2% Fluconazole on Fungal Keratitis. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1069802
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069802