Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis
Joint Authors
Guclu, Hande
Ozal, Sadık Altan
Pelitli Gurlu, Vuslat
Birgul, Ramazan
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To demonstrate the relation between optic neuritis (ON) and systemic inflammation markers as neutrophil lymphocyte ratio (N/L ratio), platelet count, mean platelet volume (MPV), and red cell distribution width (RDW) and furthermore to evaluate the utilization of these markers to predict the frequency of the ON episodes.
Methods.
Forty-two patients with acute ON and forty healthy subjects were enrolled into the study.
The medical records were reviewed for age, sex, hemoglobin (Hb), Haematocrit (Htc), RDW, platelet count, MPV, white blood cell count (WBC), neutrophil and lymphocyte count, and neutrophil lymphocyte ratio (N/L ratio).
Results.
The mean N/L ratio, platelet counts, and RDW were significantly higher in ON group ( p = 0.000 , p = 0.048 , and p = 0.002 ).
There was a significant relation between N/L ratio and number of episodes ( r = 0.492 , p = 0.001 ).
There was a statistically significant difference for MPV between one episode group and recurrent ON group ( p = 0.035 ).
Conclusions.
Simple and inexpensive laboratory methods could help us show systemic inflammation and monitor ON patients.
Higher N/L ratio can be a useful marker for predicting recurrent attacks.
American Psychological Association (APA)
Guclu, Hande& Ozal, Sadık Altan& Pelitli Gurlu, Vuslat& Birgul, Ramazan. 2015. Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069833
Modern Language Association (MLA)
Guclu, Hande…[et al.]. Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis. Journal of Ophthalmology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069833
American Medical Association (AMA)
Guclu, Hande& Ozal, Sadık Altan& Pelitli Gurlu, Vuslat& Birgul, Ramazan. Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069833
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069833