Long-Term Visual Outcome in Wet Age-Related Macular Degeneration Patients Depending on the Number of Ranibizumab Injections
Joint Authors
Torrón, C.
Leciñena, J.
Ferreras, Antonio L.
Calvo, Pilar
Ruiz-Moreno, O.
Abadia, Beatriz
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To analyse the visual outcome in wet age-related macular degeneration (AMD) patients depending on the number of ranibizumab injections.
Methods.
51 naïve wet AMD patients were retrospectively recorded.
Visual acuity (VA), central retinal thickness (CRT) measured with spectral domain (SD) optical coherence tomography (OCT), and number of intravitreal injections were compared at 6, 12, 18, 24, 30, and 36 months of follow-up.
Kaplan-Meier survival rates (SRs) based on VA outcomes were calculated depending on the number of ranibizumab injections performed.
Results.
VA improved compared with baseline at 6 and 12 months (P<0.005).
No differences were found at 18, 24, 30, and 36 months (P>0.05).
CRT measured with Cirrus OCT decreased (P<0.001) at all time points analysed.
The mean number of injections received was 6.98±3.69.
At 36 months, Kaplan-Meier SR was 76.5% (the proportion of patients without a decrease in vision of more than 0.3 logMAR units).
VA remained stable (≤0.01 logMAR units) or improved in 62.7%.
Within this group, SR was 92.9% in those who received 7 or more injections versus 51.4% receiving <7 treatments (P=0.008; log-rank test).
Conclusion.
Better VA outcomes were found in stable wet AMD patients after 3 years of follow-up if they received ≥7 ranibizumab injections.
American Psychological Association (APA)
Calvo, Pilar& Abadia, Beatriz& Ferreras, Antonio L.& Ruiz-Moreno, O.& Leciñena, J.& Torrón, C.. 2015. Long-Term Visual Outcome in Wet Age-Related Macular Degeneration Patients Depending on the Number of Ranibizumab Injections. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069851
Modern Language Association (MLA)
Calvo, Pilar…[et al.]. Long-Term Visual Outcome in Wet Age-Related Macular Degeneration Patients Depending on the Number of Ranibizumab Injections. Journal of Ophthalmology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069851
American Medical Association (AMA)
Calvo, Pilar& Abadia, Beatriz& Ferreras, Antonio L.& Ruiz-Moreno, O.& Leciñena, J.& Torrón, C.. Long-Term Visual Outcome in Wet Age-Related Macular Degeneration Patients Depending on the Number of Ranibizumab Injections. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069851
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069851