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Dye-Free Porcine Model of Experimental Branch Retinal Vein Occlusion: A Suitable Approach for Retinal Proteomics
Joint Authors
Honoré, Bent
Jørgensen Cehofski, Lasse
Kruse, Anders
Kjærgaard, Benedict
Stensballe, Allan
Vorum, Henrik
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Branch retinal vein occlusion induces complex biological processes in the retina that are generated by a multitude of interacting proteins.
These proteins and their posttranslational modifications can effectively be studied using modern proteomic techniques.
However, no method for studying large-scale protein changes following branch retinal vein occlusion has been available until now.
Obtainment of retinal tissue exposed to branch retinal vein occlusion is only available through experimental animal models.
Traditional models of experimental branch retinal vein occlusion require the use of Rose Bengal dye combined with argon laser photocoagulation.
The use of Rose Bengal dye is problematic in proteomic studies as the dye can induce multiple protein modifications when irradiated.
This paper presents a novel technique for proteomic analysis of porcine retinal tissue with branch retinal vein occlusion combining a dye-free experimental model with label-free liquid chromatography mass spectrometry based proteomics.
American Psychological Association (APA)
Jørgensen Cehofski, Lasse& Kruse, Anders& Kjærgaard, Benedict& Stensballe, Allan& Honoré, Bent& Vorum, Henrik. 2015. Dye-Free Porcine Model of Experimental Branch Retinal Vein Occlusion: A Suitable Approach for Retinal Proteomics. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069861
Modern Language Association (MLA)
Jørgensen Cehofski, Lasse…[et al.]. Dye-Free Porcine Model of Experimental Branch Retinal Vein Occlusion: A Suitable Approach for Retinal Proteomics. Journal of Ophthalmology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1069861
American Medical Association (AMA)
Jørgensen Cehofski, Lasse& Kruse, Anders& Kjærgaard, Benedict& Stensballe, Allan& Honoré, Bent& Vorum, Henrik. Dye-Free Porcine Model of Experimental Branch Retinal Vein Occlusion: A Suitable Approach for Retinal Proteomics. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069861
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069861