Comparison of Physiologic versus Pharmacologic Mydriasis on Anterior Chamber Angle Measurements Using Spectral Domain Optical Coherence Tomography
Joint Authors
Dastiridou, Anna I.
Pan, Xiaojing
Zhang, ZhouYuan
Marion, Kenneth M.
Chopra, Vikas
Francis, Brian A.
Sadda, Srinivas R.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To compare the effects of physiologic versus pharmacologic pupil dilation on anterior chamber angle (ACA) measurements obtained with spectral domain optical coherence tomography (SD-OCT).
Methods.
Forty eyes from 20 healthy, phakic individuals with open angles underwent anterior segment OCT imaging under 3 pupillary states: (1) pupil constricted under standard room lighting, (2) physiologic mydriasis in a darkened room, and (3) postpharmacologic mydriasis.
Inferior angle Schwalbe’s line-angle opening distance (SL-AOD) and SL-trabecular-iris-space area (SL-TISA) were computed for each eye and pupillary condition by masked, certified Reading Center graders using customized grading software.
Results.
SL-AOD and SL-TISA under pupillary constriction to room light were 0.87±0.31 mm and 0.33±0.14 mm2, respectively; decreased to 0.75±0.29 mm P<0.01 and 0.29±0.13 mm2 P<0.01, respectively, under physiologic mydriasis; and increased to 0.90±0.38 mm P<0.01 and 0.34±0.17 mm2 P=0.06 under pharmacologic mydriasis compared to baseline.
Conclusions.
Using SD-OCT imaging, pharmacologic mydriasis yielded the widest angle opening, whereas physiologic mydriasis yielded the most angle narrowing in normal individuals with open iridocorneal angles.
Accounting for the state of the pupil and standardizing the lighting condition would appear to be of importance for future studies of the angle.
American Psychological Association (APA)
Dastiridou, Anna I.& Pan, Xiaojing& Zhang, ZhouYuan& Marion, Kenneth M.& Francis, Brian A.& Sadda, Srinivas R.…[et al.]. 2015. Comparison of Physiologic versus Pharmacologic Mydriasis on Anterior Chamber Angle Measurements Using Spectral Domain Optical Coherence Tomography. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069864
Modern Language Association (MLA)
Dastiridou, Anna I.…[et al.]. Comparison of Physiologic versus Pharmacologic Mydriasis on Anterior Chamber Angle Measurements Using Spectral Domain Optical Coherence Tomography. Journal of Ophthalmology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1069864
American Medical Association (AMA)
Dastiridou, Anna I.& Pan, Xiaojing& Zhang, ZhouYuan& Marion, Kenneth M.& Francis, Brian A.& Sadda, Srinivas R.…[et al.]. Comparison of Physiologic versus Pharmacologic Mydriasis on Anterior Chamber Angle Measurements Using Spectral Domain Optical Coherence Tomography. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069864
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069864