Clinical Outcome of Hypertensive Uveitis

Abstract EN

Purpose.

To review the clinical outcome of patients with hypertensive uveitis.

Methods.

Retrospective review of uveitis patients with elevated intraocular pressure (IOP) > 25 mmHg and >1-year follow-up.

Data are uveitis type, etiology, viral (VU) and nonviral uveitis (NVU), IOP, and medical and/or surgical treatment.

Results.

In 61 patients, IOP values are first 32.9 mmHg (SD: 9.0), highest 36.6 mmHg (SD: 9.9), 3 months after the first episode 19.54 mmHg (SD: 9.16), and end of follow-up 15.5 mmHg (SD: 6.24).

Patients with VU ( n = 25 ) were older (50.6 y/35.7 y, p = 0.014 ) and had more unilateral disease (100%/72.22% p = 0.004 ) than those with NVU ( n = 36 ).

Thirty patients (49.2%) had an elevated IOP before topical corticosteroid treatment.

Patients with viral uveitis might have higher first elevated IOP (36.0/27.5 mmHg, p = 0,008 ) and maximal IOP (40.28/34.06 mmHg, p = 0.0148 ) but this was not significant when limited to the measurements before the use of topical corticosteroids ( p = 0.260 and 0.160).

Glaucoma occurred in 15 patients (24.59%) and was suspected in 11 (18.03%) without difference in viral and nonviral groups ( p = 0.774 ).

Conclusion.

Patients with VU were older and had more unilateral hypertensive uveitis.

Glaucoma frequently complicates hypertensive uveitis.

Half of the patients had an elevated IOP before topical corticosteroid treatment.