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An Evaluation of Effects of Different Mydriatics on Choroidal Thickness by Examining Anterior Chamber Parameters: The Scheimpflug Imaging and Enhanced Depth Imaging-OCT Study
Joint Authors
Atas, Mustafa
Demircan, Suleyman
Yuvacı, İsa
Pangal, Emine
Başkan, Burhan
Yuvacı, Sümeyra
Bayram, Nurettin
Akal, Ali
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
To assess the effects of mydriatics commonly used in clinical practice on choroidal thickness and anterior chamber change.
Methods.
This was a prospective, randomized, controlled, double-blinded study including a single eye of the participants.
The subjects were assigned into 4 groups to receive tropicamide 1%, phenylephrine 2.5%, cyclopentolate 1%, and artificial tears.
At the baseline, anterior chamber parameters were assessed using a Pentacam Scheimpflug camera system, and choroidal thickness (CT) was measured using a spectral-domain OCT with Enhanced Depth Imaging (EDI) modality.
All measurements were repeated again after drug administration.
Results.
Increases in pupil diameter, volume, and depth of anterior chamber were found to be significant (p=0.000, p=0.000, and p=0.000, resp.), while decreases in the choroidal thickness were found to be significant in subjects receiving mydriatics (p<0.05).
Conclusions.
The study has shown that while cyclopentolate, tropicamide, and phenylephrine cause a decrease in choroidal thickness, they also lead to an increase in the volume and depth of anterior chamber.
However, no correlation was detected between anterior chamber parameters and choroidal changes after drug administration.
These findings suggest that the mydriatics may affect the choroidal thickness regardless of anterior chamber parameters.
This study was registered with trial registration number 2014/357.
American Psychological Association (APA)
Yuvacı, İsa& Pangal, Emine& Yuvacı, Sümeyra& Bayram, Nurettin& Atas, Mustafa& Başkan, Burhan…[et al.]. 2015. An Evaluation of Effects of Different Mydriatics on Choroidal Thickness by Examining Anterior Chamber Parameters: The Scheimpflug Imaging and Enhanced Depth Imaging-OCT Study. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069904
Modern Language Association (MLA)
Yuvacı, İsa…[et al.]. An Evaluation of Effects of Different Mydriatics on Choroidal Thickness by Examining Anterior Chamber Parameters: The Scheimpflug Imaging and Enhanced Depth Imaging-OCT Study. Journal of Ophthalmology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1069904
American Medical Association (AMA)
Yuvacı, İsa& Pangal, Emine& Yuvacı, Sümeyra& Bayram, Nurettin& Atas, Mustafa& Başkan, Burhan…[et al.]. An Evaluation of Effects of Different Mydriatics on Choroidal Thickness by Examining Anterior Chamber Parameters: The Scheimpflug Imaging and Enhanced Depth Imaging-OCT Study. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069904
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069904