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Effectiveness Evaluation of Levamisole, Albendazole, Ivermectin, and Vernonia amygdalina in West African Dwarf Goats
Joint Authors
Adediran, Oyeduntan Adejoju
Uwalaka, Emmanuel Chibuike
Source
Journal of Parasitology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Anthelmintic drug resistance has led to the search for alternatives in controlling helminth infections.
Fifty West African Dwarf goats without history of anthelmintic treatment were divided equally into five groups.
Group A was treated with ivermectin injection subcutaneously, group B with levamisole subcutaneously, group C with albendazole orally, and group D with aqueous extract of Vernonia amygdalina and group E was untreated control.
Faecal samples were collected before treatment from each animal and larval culture was carried out.
Faecal egg count reduction (FECR) test was carried out for each group and the data analysed using FECR version 4 to calculate percent reduction in faecal egg count.
Predominant helminth infections from larval culture were Haemonchus contortus (70%), Trichostrongylus spp.
(61%), and Oesophagostomum spp.
(56%).
Mixed infection was present in all the animals.
From the FECR test Vernonia amygdalina extract was more effective against helminths (100%), compared to ivermectin 96%, levamisole 96%, and albendazole 99%.
The lower 95% confidence limit was 89 for ivermectin and levamisole and 91 for albendazole.
There is low resistance to ivermectin and levamisole and susceptibility to albendazole while V.
amygdalina has great potentials that could be explored for the treatment of helminth diseases in goats.
American Psychological Association (APA)
Adediran, Oyeduntan Adejoju& Uwalaka, Emmanuel Chibuike. 2015. Effectiveness Evaluation of Levamisole, Albendazole, Ivermectin, and Vernonia amygdalina in West African Dwarf Goats. Journal of Parasitology Research،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069972
Modern Language Association (MLA)
Adediran, Oyeduntan Adejoju& Uwalaka, Emmanuel Chibuike. Effectiveness Evaluation of Levamisole, Albendazole, Ivermectin, and Vernonia amygdalina in West African Dwarf Goats. Journal of Parasitology Research No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069972
American Medical Association (AMA)
Adediran, Oyeduntan Adejoju& Uwalaka, Emmanuel Chibuike. Effectiveness Evaluation of Levamisole, Albendazole, Ivermectin, and Vernonia amygdalina in West African Dwarf Goats. Journal of Parasitology Research. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1069972