Noninvasive Superoxide Monitoring of In Vitro Neuronal Differentiation Using a Cell-Based Biosensor
Joint Authors
Moschopoulou, Georgia
Kintzios, Spyridon
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Membrane-engineered cells bearing superoxide dismutase (SOD) molecules on their surface offer the capability of ultrarapid and ultrasensitive detection of the superoxide anion (O2-) through the measurement of changes of their cell membrane potential.
We herewith report the application of this technology for the noninvasive determination of superoxide levels during the in vitro differentiation of PC12 cells.
We were able to detect changes in O2- accumulation in the culture medium, which were closely associated with the progress of neuronal differentiation.
American Psychological Association (APA)
Moschopoulou, Georgia& Kintzios, Spyridon. 2015. Noninvasive Superoxide Monitoring of In Vitro Neuronal Differentiation Using a Cell-Based Biosensor. Journal of Sensors،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1070195
Modern Language Association (MLA)
Moschopoulou, Georgia& Kintzios, Spyridon. Noninvasive Superoxide Monitoring of In Vitro Neuronal Differentiation Using a Cell-Based Biosensor. Journal of Sensors No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1070195
American Medical Association (AMA)
Moschopoulou, Georgia& Kintzios, Spyridon. Noninvasive Superoxide Monitoring of In Vitro Neuronal Differentiation Using a Cell-Based Biosensor. Journal of Sensors. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1070195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1070195