Alternative Living Kidney Donation Programs Boost Genetically Unrelated Donation
Joint Authors
Betjes, Michiel G. H.
Laging, Mirjam
van Agteren, Madelon
Poldervaart, Rosalie A.
Royaards, Tessa
Kal-van Gestel, Judith A.
de Klerk, Marry
Roodnat, Joke I.
Zuidema, Willij
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Donor-recipient ABO and/or HLA incompatibility used to lead to donor decline.
Development of alternative transplantation programs enabled transplantation of incompatible couples.
How did that influence couple characteristics? Between 2000 and 2014, 1232 living donor transplantations have been performed.
In conventional and ABO-incompatible transplantation the willing donor becomes an actual donor for the intended recipient.
In kidney-exchange and domino-donation the donor donates indirectly to the intended recipient.
The relationship between the donor and intended recipient was studied.
There were 935 conventional and 297 alternative program transplantations.
There were 66 ABO-incompatible, 68 domino-paired, 62 kidney-exchange, and 104 altruistic donor transplantations.
Waiting list recipients (n=101) were excluded as they did not bring a living donor.
1131 couples remained of whom 196 participated in alternative programs.
Genetically unrelated donors (486) were primarily partners.
Genetically related donors (645) were siblings, parents, children, and others.
Compared to genetically related couples, almost three times as many genetically unrelated couples were incompatible and participated in alternative programs (P<0.001).
62% of couples were genetically related in the conventional donation program versus 32% in alternative programs (P<0.001).
Patient and graft survival were not significantly different between recipient programs.
Alternative donation programs increase the number of transplantations by enabling genetically unrelated donors to donate.
American Psychological Association (APA)
Poldervaart, Rosalie A.& Laging, Mirjam& Royaards, Tessa& Kal-van Gestel, Judith A.& van Agteren, Madelon& de Klerk, Marry…[et al.]. 2015. Alternative Living Kidney Donation Programs Boost Genetically Unrelated Donation. Journal of Transplantation،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1070440
Modern Language Association (MLA)
Poldervaart, Rosalie A.…[et al.]. Alternative Living Kidney Donation Programs Boost Genetically Unrelated Donation. Journal of Transplantation No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1070440
American Medical Association (AMA)
Poldervaart, Rosalie A.& Laging, Mirjam& Royaards, Tessa& Kal-van Gestel, Judith A.& van Agteren, Madelon& de Klerk, Marry…[et al.]. Alternative Living Kidney Donation Programs Boost Genetically Unrelated Donation. Journal of Transplantation. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1070440
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1070440