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Risk Factors Associated with Increased Morbidity in Living Liver Donation
Joint Authors
Pugliese, Renata Pereira Sustovich
Candido, Helry L.
da Fonseca, Eduardo A.
Feier, Flávia H.
Benavides, Marcel A.
Silva, Enis D.
Gordon, Karina
de Abreu, Marcelo Gama
Canet, Jaume
Chapchap, Paulo
Neto, Joao Seda
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Living donor liver donation (LDLD) is an alternative to cadaveric liver donation.
We aimed at identifying risk factors and developing a score for prediction of postoperative complications (POCs) after LDLD in donors.
This is a retrospective cohort study in 688 donors between June 1995 and February 2014 at Hospital Sírio-Libanês and A.C.
Camargo Cancer Center, in São Paulo, Brazil.
Primary outcome was POC graded ≥III according to the Clavien-Dindo classification.
Left lateral segment (LLS), left lobe (LL), and right lobe resections (RL) were conducted in 492 (71.4%), 109 (15.8%), and 87 (12.6%) donors, respectively.
In total, 43 (6.2%) developed POCs, which were more common after RL than LLS and LL (14/87 (16.1%) versus 23/492 (4.5%) and 6/109 (5.5%), resp., p < 0.001 ).
Multivariate analysis showed that RL resection (OR: 2.81, 95% CI: 1.32 to 3.01; p = 0.008 ), smoking status (OR: 3.2, 95% CI: 1.35 to 7.56; p = 0.012 ), and blood transfusion (OR: 3.15, 95% CI: 1.45 to 6.84; p = 0.004 ) were independently associated with POCs.
RL resection, intraoperative blood transfusion, and smoking were associated with increased risk for POCs in donors.
American Psychological Association (APA)
Candido, Helry L.& da Fonseca, Eduardo A.& Feier, Flávia H.& Pugliese, Renata Pereira Sustovich& Benavides, Marcel A.& Silva, Enis D.…[et al.]. 2015. Risk Factors Associated with Increased Morbidity in Living Liver Donation. Journal of Transplantation،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1070445
Modern Language Association (MLA)
Candido, Helry L.…[et al.]. Risk Factors Associated with Increased Morbidity in Living Liver Donation. Journal of Transplantation No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1070445
American Medical Association (AMA)
Candido, Helry L.& da Fonseca, Eduardo A.& Feier, Flávia H.& Pugliese, Renata Pereira Sustovich& Benavides, Marcel A.& Silva, Enis D.…[et al.]. Risk Factors Associated with Increased Morbidity in Living Liver Donation. Journal of Transplantation. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1070445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1070445