Cytokines as Mediators of Pain-Related Process in Breast Cancer
Joint Authors
Panis, Carolina
Pavanelli, Wander Rogério
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Pain is a clinical sign of inflammation found in a wide variety of chronic pathologies, including cancer.
The occurrence of pain in patients carrying breast tumors is reported and is associated with aspects concerning disease spreading, treatment, and surgical intervention.
The persistence of pain in patients submitted to breast surgery is estimated in a range from 21% to 55% and may affect patients before and after surgery.
Beyond the physical compression exerted by the metastatic mass expansion and tissue injury found in breast cancer, inflammatory components that are significantly produced by the host-tumor interaction can significantly contribute to the generation of pain.
In this context, cytokines have been studied aiming to establish a cause-effect relationship in cancer pain-related syndromes, especially the proinflammatory ones.
Few reports have investigated the relationship between pain and cytokines in women carrying advanced breast cancer.
In this scenario, the present review analyzes the main cytokines produced in breast cancer and discusses the evidences from literature regarding its role in specific clinical features related with this pathology.
American Psychological Association (APA)
Panis, Carolina& Pavanelli, Wander Rogério. 2015. Cytokines as Mediators of Pain-Related Process in Breast Cancer. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1072127
Modern Language Association (MLA)
Panis, Carolina& Pavanelli, Wander Rogério. Cytokines as Mediators of Pain-Related Process in Breast Cancer. Mediators of Inflammation No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1072127
American Medical Association (AMA)
Panis, Carolina& Pavanelli, Wander Rogério. Cytokines as Mediators of Pain-Related Process in Breast Cancer. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1072127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072127