Role of COX-2mPGES-1Prostaglandin E2 Cascade in Kidney Injury
Joint Authors
Ding, Guixia
Zhang, Yue
Heiney, Kristina Marie
Huang, Songming
Zhang, Aihua
Jia, Zhanjun
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
COX-2/mPGES-1/PGE2 cascade plays critical roles in modulating many physiological and pathological actions in different organs.
In the kidney, this cascade is of high importance in regulating fluid metabolism, blood pressure, and renal hemodynamics.
Under some disease conditions, this cascade displays various actions in response to the different pathological insults.
In the present review, the roles of this cascade in the pathogenesis of kidney injuries including diabetic and nondiabetic kidney diseases and acute kidney injuries were introduced and discussed.
The new insights from this review not only increase the understanding of the pathological role of the COX-2/mPGES-1/PGE2 pathway in kidney injuries, but also shed new light on the innovation of the strategies for the treatment of kidney diseases.
American Psychological Association (APA)
Jia, Zhanjun& Zhang, Yue& Ding, Guixia& Heiney, Kristina Marie& Huang, Songming& Zhang, Aihua. 2015. Role of COX-2mPGES-1Prostaglandin E2 Cascade in Kidney Injury. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1072155
Modern Language Association (MLA)
Jia, Zhanjun…[et al.]. Role of COX-2mPGES-1Prostaglandin E2 Cascade in Kidney Injury. Mediators of Inflammation No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1072155
American Medical Association (AMA)
Jia, Zhanjun& Zhang, Yue& Ding, Guixia& Heiney, Kristina Marie& Huang, Songming& Zhang, Aihua. Role of COX-2mPGES-1Prostaglandin E2 Cascade in Kidney Injury. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1072155
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072155