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Virological Mechanisms in the Coinfection between HIV and HCV
Joint Authors
Torti, Carlo
Focà, Alfredo
Zicca, Emilia
Pavia, Grazia
Marascio, Nadia
Liberto, Maria Carla
Quirino, Angela
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Due to shared transmission routes, coinfection with Hepatitis C Virus (HCV) is common in patients infected by Human Immunodeficiency Virus (HIV).
The immune-pathogenesis of liver disease in HIV/HCV coinfected patients is a multifactorial process.
Several studies demonstrated that HIV worsens the course of HCV infection, increasing the risk of cirrhosis and hepatocellular carcinoma.
Also, HCV might increase immunological defects due to HIV and risk of comorbidities.
A specific cross-talk among HIV and HCV proteins in coinfected patients modulates the natural history, the immune responses, and the life cycle of both viruses.
These effects are mediated by immune mechanisms and by a cross-talk between the two viruses which could interfere with host defense mechanisms.
In this review, we focus on some virological/immunological mechanisms of the pathogenetic interactions between HIV and HCV in the human host.
American Psychological Association (APA)
Liberto, Maria Carla& Zicca, Emilia& Pavia, Grazia& Quirino, Angela& Marascio, Nadia& Torti, Carlo…[et al.]. 2015. Virological Mechanisms in the Coinfection between HIV and HCV. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072247
Modern Language Association (MLA)
Liberto, Maria Carla…[et al.]. Virological Mechanisms in the Coinfection between HIV and HCV. Mediators of Inflammation No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1072247
American Medical Association (AMA)
Liberto, Maria Carla& Zicca, Emilia& Pavia, Grazia& Quirino, Angela& Marascio, Nadia& Torti, Carlo…[et al.]. Virological Mechanisms in the Coinfection between HIV and HCV. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072247
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072247