Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells
Joint Authors
Baños-Lara, Ma. Del Rocío
Piao, Boyang
Guerrero-Plata, Antonieta
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Mucins (MUC) constitute an important component of the inflammatory and innate immune response.
However, the expression of these molecules by respiratory viral infections is still largely unknown.
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two close-related paramyxoviruses that can cause severe low respiratory tract disease in infants and young children worldwide.
Currently, there is not vaccine available for neither virus.
In this work, we explored the differential expression of MUC by RSV and hMPV in human epithelial cells.
Our data indicate that the MUC expression by RSV and hMPV differs significantly, as we observed a stronger induction of MUC8, MUC15, MUC20, MUC21, and MUC22 by RSV infection while the expression of MUC1, MUC2, and MUC5B was dominated by the infection with hMPV.
These results may contribute to the different immune response induced by these two respiratory viruses.
American Psychological Association (APA)
Baños-Lara, Ma. Del Rocío& Piao, Boyang& Guerrero-Plata, Antonieta. 2015. Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072257
Modern Language Association (MLA)
Baños-Lara, Ma. Del Rocío…[et al.]. Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells. Mediators of Inflammation No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1072257
American Medical Association (AMA)
Baños-Lara, Ma. Del Rocío& Piao, Boyang& Guerrero-Plata, Antonieta. Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072257
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072257