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Sterile Inflammation in Drosophila
Joint Authors
Shaukat, Zeeshan
Liu, Dawei
Gregory, Stephen
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The study of immune responses in Drosophila has already yielded significant results with impacts on our understanding of vertebrate immunity, such as the characterization of the Toll receptor.
Several recent papers have focused on the humoral response to damage signals rather than pathogens, particularly damage signals from tumour-like tissues generated by loss of cell polarity or chromosomal instability.
Both the triggers that generate this sterile inflammation and the systemic and local effects of it are only just beginning to be characterized in Drosophila.
Here we review the molecular mechanisms that are known that give rise to the recruitment of Drosophila phagocytes, called hemocytes, as well as the signals, such as TNFα, that stimulated hemocytes emit at sites of perceived damage.
The signalling consequences of inflammation, such as the activation of JNK, and the potential for modifying this response are also discussed.
American Psychological Association (APA)
Shaukat, Zeeshan& Liu, Dawei& Gregory, Stephen. 2015. Sterile Inflammation in Drosophila. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072283
Modern Language Association (MLA)
Shaukat, Zeeshan…[et al.]. Sterile Inflammation in Drosophila. Mediators of Inflammation No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1072283
American Medical Association (AMA)
Shaukat, Zeeshan& Liu, Dawei& Gregory, Stephen. Sterile Inflammation in Drosophila. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072283
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072283