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Cancer Microenvironment and Endoplasmic Reticulum Stress Response
Joint Authors
Petrungaro, Simonetta
Conti, Silvia
Facchiano, Antonio
Ziparo, Elio
Filippini, Antonio
Giampietri, Claudia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-27
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Different stressful conditions such as hypoxia, nutrient deprivation, pH changes, or reduced vascularization, potentially able to act as growth-limiting factors for tumor cells, activate the unfolded protein response (UPR).
UPR is therefore involved in tumor growth and adaptation to severe environments and is generally cytoprotective in cancer.
The present review describes the molecular mechanisms underlying UPR and able to promote survival and proliferation in cancer.
The critical role of UPR activation in tumor growth promotion is discussed in detail for a few paradigmatic tumors such as prostate cancer and melanoma.
American Psychological Association (APA)
Giampietri, Claudia& Petrungaro, Simonetta& Conti, Silvia& Facchiano, Antonio& Filippini, Antonio& Ziparo, Elio. 2015. Cancer Microenvironment and Endoplasmic Reticulum Stress Response. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1072317
Modern Language Association (MLA)
Giampietri, Claudia…[et al.]. Cancer Microenvironment and Endoplasmic Reticulum Stress Response. Mediators of Inflammation No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1072317
American Medical Association (AMA)
Giampietri, Claudia& Petrungaro, Simonetta& Conti, Silvia& Facchiano, Antonio& Filippini, Antonio& Ziparo, Elio. Cancer Microenvironment and Endoplasmic Reticulum Stress Response. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1072317
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072317