Pathophysiological Role of Extracellular Purinergic Mediators in the Control of Intestinal Inflammation
Joint Authors
Kurashima, Yosuke
Kiyono, Hiroshi
Kunisawa, Jun
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purinergic mediators such as adenosine 5′-triphosphate (ATP) are released into the extracellular compartment from damaged tissues and activated immune cells.
They are then recognized by multiple purinergic P2X and P2Y receptors.
Release and recognition of extracellular ATP are associated with both the development and the resolution of inflammation and infection.
Accumulating evidence has recently suggested the potential of purinergic receptors as novel targets for drugs for treating intestinal disorders, including intestinal inflammation and irritable bowel syndrome.
In this review, we highlight recent findings regarding the pathophysiological role of purinergic mediators in the development of intestinal inflammation.
American Psychological Association (APA)
Kurashima, Yosuke& Kiyono, Hiroshi& Kunisawa, Jun. 2015. Pathophysiological Role of Extracellular Purinergic Mediators in the Control of Intestinal Inflammation. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1072323
Modern Language Association (MLA)
Kurashima, Yosuke…[et al.]. Pathophysiological Role of Extracellular Purinergic Mediators in the Control of Intestinal Inflammation. Mediators of Inflammation No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1072323
American Medical Association (AMA)
Kurashima, Yosuke& Kiyono, Hiroshi& Kunisawa, Jun. Pathophysiological Role of Extracellular Purinergic Mediators in the Control of Intestinal Inflammation. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1072323
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072323