The Sterile Inflammation in the Exacerbation of HBV-Associated Liver Injury
Joint Authors
Yang, Qiao
Shi, Yu
Yang, Ying
Lou, Guohua
Chen, Zhi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-29
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Exacerbation of hepatitis B virus-associated liver injury is characterized by abnormal immune response which not only mobilizes specific antiviral effects but also poses a potentially lethal nonspecific sterile inflammation to the host.
How nonspecific sterile inflammation is triggered after the preexisting injury caused by specific immune injury remains elusive.
In the setting of sterile inflammation, endogenous damage-associated molecular patterns are released by stressed and dying hepatocytes, which alarm the immune system through their potential pattern recognition receptors and related signaling pathways, orchestrate the influx of diverse cytokines, and ultimately amplify liver destruction.
This review highlights current knowledge about the sterile hepatic inflammation in the exacerbation of chronic hepatitis B.
American Psychological Association (APA)
Yang, Qiao& Shi, Yu& Yang, Ying& Lou, Guohua& Chen, Zhi. 2015. The Sterile Inflammation in the Exacerbation of HBV-Associated Liver Injury. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1072391
Modern Language Association (MLA)
Yang, Qiao…[et al.]. The Sterile Inflammation in the Exacerbation of HBV-Associated Liver Injury. Mediators of Inflammation No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1072391
American Medical Association (AMA)
Yang, Qiao& Shi, Yu& Yang, Ying& Lou, Guohua& Chen, Zhi. The Sterile Inflammation in the Exacerbation of HBV-Associated Liver Injury. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1072391
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072391