Cancer as a Proinflammatory Environment: Metastasis and Cachexia
Joint Authors
Alcântara, Paulo S. M.
Ottoch, José P.
Inácio Pinto, Nelson
Carnier, June
Tokeshi, Flavio
Oller do Nascimento, Claudia Maria da Penha
Oyama, Lila Missae
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The development of the syndrome of cancer cachexia and that of metastasis are related with a poor prognostic for cancer patients.
They are considered multifactorial processes associated with a proinflammatory environment, to which tumour microenvironment and other tissues from the tumour bearing individuals contribute.
The aim of the present review is to address the role of ghrelin, myostatin, leptin, HIF, IL-6, TNF-α, and ANGPTL-4 in the regulation of energy balance, tumour development, and tumoural cell invasion.
Hypoxia induced factor plays a prominent role in tumour macro- and microenvironment, by modulating the release of proinflammatory cytokines.
American Psychological Association (APA)
Inácio Pinto, Nelson& Carnier, June& Oyama, Lila Missae& Ottoch, José P.& Alcântara, Paulo S. M.& Tokeshi, Flavio…[et al.]. 2015. Cancer as a Proinflammatory Environment: Metastasis and Cachexia. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1072561
Modern Language Association (MLA)
Inácio Pinto, Nelson…[et al.]. Cancer as a Proinflammatory Environment: Metastasis and Cachexia. Mediators of Inflammation No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1072561
American Medical Association (AMA)
Inácio Pinto, Nelson& Carnier, June& Oyama, Lila Missae& Ottoch, José P.& Alcântara, Paulo S. M.& Tokeshi, Flavio…[et al.]. Cancer as a Proinflammatory Environment: Metastasis and Cachexia. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1072561
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072561
