Role of IL-38 and Its Related Cytokines in Inflammation
Joint Authors
Yuan, Xianli
Peng, Xiao
Li, Yan
Li, Mingcai
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Interleukin- (IL-) 38 is a recently discovered cytokine and is the tenth member of the IL-1 cytokine family.
IL-38 shares structural features with IL-1 receptor antagonist (IL-1Ra) and IL-36Ra.
IL-36R is the specific receptor of IL-38, a partial receptor antagonist of IL-36.
IL-38 inhibits the production of T-cell cytokines IL-17 and IL-22.
IL-38 also inhibits the production of IL-8 induced by IL-36γ, thus inhibiting inflammatory responses.
IL-38-related cytokines, including IL-1Ra and IL-36Ra, are involved in the regulation of inflammation and immune responses.
The study of IL-38 and IL-38-related cytokines might provide new insights for developing anti-inflammatory treatments in the near future.
American Psychological Association (APA)
Yuan, Xianli& Peng, Xiao& Li, Yan& Li, Mingcai. 2015. Role of IL-38 and Its Related Cytokines in Inflammation. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072587
Modern Language Association (MLA)
Yuan, Xianli…[et al.]. Role of IL-38 and Its Related Cytokines in Inflammation. Mediators of Inflammation No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1072587
American Medical Association (AMA)
Yuan, Xianli& Peng, Xiao& Li, Yan& Li, Mingcai. Role of IL-38 and Its Related Cytokines in Inflammation. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072587
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072587
