IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients
Joint Authors
Pitta, Ivan da Rocha
de Melo Rego, Moacyr Jesus Barreto
Oliveira, Priscilla Stela Santana de
Pereira, Michelly Cristiny
Cardoso, Pablo Ramon Gualberto
Lima, Emerson Vasconcelos de Andrade
Pitta, Maira Galdino da Rocha
Duarte, Ângela Luzia Branco Pinto
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Psoriasis is a chronic inflammatory skin disease characterized by alterations in cytokines produced by both Th1 and Th17 pathways.
The aim of this study was to evaluate serum levels of pivotal cytokines and correlate them with clinical parameters.
Serum samples from 53 psoriasis patients and 35 healthy volunteers, matched by the proportion of sex and age ratios, were collected for ELISA cytokine detection.
Psoriasis Area and Severity Index (PASI) was assessed at the time of sampling in psoriasis patients.
Our findings demonstrate that IL-17A, IL-22, and IL-6 serum concentrations were significantly higher in psoriasis patients than in the control group.
No statistical correlation could be found between cytokines concentrations, PASI score, and age in this study.
Although our results do not show any correlation between serum levels of IL-17A, IL-22, and IL-6 and disease activity, the present study confirms that they were increased in Brazilian psoriasis patients in comparison to healthy volunteers.
American Psychological Association (APA)
Oliveira, Priscilla Stela Santana de& Cardoso, Pablo Ramon Gualberto& Lima, Emerson Vasconcelos de Andrade& Pereira, Michelly Cristiny& Duarte, Ângela Luzia Branco Pinto& Pitta, Ivan da Rocha…[et al.]. 2015. IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1072592
Modern Language Association (MLA)
Oliveira, Priscilla Stela Santana de…[et al.]. IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients. Mediators of Inflammation No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1072592
American Medical Association (AMA)
Oliveira, Priscilla Stela Santana de& Cardoso, Pablo Ramon Gualberto& Lima, Emerson Vasconcelos de Andrade& Pereira, Michelly Cristiny& Duarte, Ângela Luzia Branco Pinto& Pitta, Ivan da Rocha…[et al.]. IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1072592
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072592
