The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease
Joint Authors
Nagy, György
Marton, Nikolett
Baricza, Eszter
Érsek, Barbara
Buzás, Edit
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Although Src-like adaptor proteins (SLAP-1 and SLAP-2) were mainly studied in lymphocytes, where they act as negative regulators and provide fine control of receptor signaling, recently, several other functions of these proteins were discovered.
In addition to the well-characterized immunoregulatory functions, SLAP proteins appear to have an essential role in the pathogenesis of type I hypersensitivity, osteoporosis, and numerous malignant diseases.
Both adaptor proteins are expressed in a wide variety of tissues, where they have mostly inhibitory effects on multiple intracellular signaling pathways.
In this review, we summarize the diverse effects of SLAP proteins.
American Psychological Association (APA)
Marton, Nikolett& Baricza, Eszter& Érsek, Barbara& Buzás, Edit& Nagy, György. 2015. The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1072660
Modern Language Association (MLA)
Marton, Nikolett…[et al.]. The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease. Mediators of Inflammation No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1072660
American Medical Association (AMA)
Marton, Nikolett& Baricza, Eszter& Érsek, Barbara& Buzás, Edit& Nagy, György. The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1072660
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072660
