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Selected Inflammatory and Metabolic Markers in Psoriatic Patients Treated with Goeckerman Therapy
Joint Authors
Kremláček, J.
Borska, Lenka
Fiala, Zdenek
Kondelkova, Katerina
Hamakova, Kvetoslava
Rendarova, Simona
Rehacek, Vit
Krejsek, Jan
Andrys, Ctirad
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines.
Goeckerman therapy (GT) represents an effective treatment of psoriasis.
This study evaluated variation of selected inflammatory and metabolic markers during GT and the relationships between the markers, severity of the disease (PASI score), body mass, and the basic characteristics of the therapy.
The study was conducted on a group of patients (n=32) and on a control group (n=24).
Before GT, we found significantly elevated levels of proinflammatory CRP (p<0.001) and leptin (p<0.05) in psoriatic patients (compared to the controls).
The therapy significantly decreased the levels of CRP and adiponectin.
We found positive correlations between CRP and total duration of GT (p<0.05) and CRP and the time of UV exposure (p<0.01) and negative correlations between adiponectin and the total duration of GT (p<0.05) and adiponectin and the application of CCT ointment (p<0.001).
From our results, we can conclude that GT causes partial reduction of both proinflammatory and anti-inflammatory markers.
However, the levels of proinflammatory CRP and leptin remained significantly higher in the patients than in the control group.
American Psychological Association (APA)
Kondelkova, Katerina& Borska, Lenka& Andrys, Ctirad& Krejsek, Jan& Hamakova, Kvetoslava& Rendarova, Simona…[et al.]. 2015. Selected Inflammatory and Metabolic Markers in Psoriatic Patients Treated with Goeckerman Therapy. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1072672
Modern Language Association (MLA)
Kondelkova, Katerina…[et al.]. Selected Inflammatory and Metabolic Markers in Psoriatic Patients Treated with Goeckerman Therapy. Mediators of Inflammation No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1072672
American Medical Association (AMA)
Kondelkova, Katerina& Borska, Lenka& Andrys, Ctirad& Krejsek, Jan& Hamakova, Kvetoslava& Rendarova, Simona…[et al.]. Selected Inflammatory and Metabolic Markers in Psoriatic Patients Treated with Goeckerman Therapy. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1072672
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072672