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Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An eLORETA Controlled Study on Resting States
Joint Authors
Paraskevopoulos, Evangelos
Styliadis, Charis
Kartsidis, Panagiotis
Ioannides, Andreas A.
Bamidis, Panagiotis D.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-07
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The present study investigates whether a combined cognitive and physical training may induce changes in the cortical activity as measured via electroencephalogram (EEG) and whether this change may index a deceleration of pathological processes of brain aging.
Seventy seniors meeting the clinical criteria of mild cognitive impairment (MCI) were equally divided into 5 groups: 3 experimental groups engaged in eight-week cognitive and/or physical training and 2 control groups: active and passive.
A 5-minute long resting state EEG was measured before and after the intervention.
Cortical EEG sources were modelled by exact low resolution brain electromagnetic tomography (eLORETA).
Cognitive function was assessed before and after intervention using a battery of neuropsychological tests including the minimental state examination (MMSE).
A significant training effect was identified only after the combined training scheme: a decrease in the post- compared to pre-training activity of precuneus/posterior cingulate cortex in delta, theta, and beta bands.
This effect was correlated to improvements in cognitive capacity as evaluated by MMSE scores.
Our results indicate that combined physical and cognitive training shows indices of a positive neuroplastic effect in MCI patients and that EEG may serve as a potential index of gains versus cognitive declines and neurodegeneration.
This trial is registered with ClinicalTrials.gov Identifier NCT02313935.
American Psychological Association (APA)
Styliadis, Charis& Kartsidis, Panagiotis& Paraskevopoulos, Evangelos& Ioannides, Andreas A.& Bamidis, Panagiotis D.. 2015. Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An eLORETA Controlled Study on Resting States. Neural Plasticity،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075299
Modern Language Association (MLA)
Styliadis, Charis…[et al.]. Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An eLORETA Controlled Study on Resting States. Neural Plasticity No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1075299
American Medical Association (AMA)
Styliadis, Charis& Kartsidis, Panagiotis& Paraskevopoulos, Evangelos& Ioannides, Andreas A.& Bamidis, Panagiotis D.. Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An eLORETA Controlled Study on Resting States. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075299
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075299