Audiomotor Integration in Minimally Conscious State: Proof of Concept!
Joint Authors
Naro, Antonino
Leo, Antonino
Cannavò, Antonino
Buda, Antonio
Bruno, Rocco
Salviera, Carlo
Bramanti, Placido
Calabrò, Rocco Salvatore
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-03
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Patients suffering from chronic disorders of consciousness (DOC) are characterized by profound unawareness and an impairment of large-scale cortical and subcortical connectivity.
In this study, we applied an electrophysiological approach aimed at identifying the residual audiomotor connectivity patterns that are thought to be linked to awareness.
We measured some markers of audiomotor integration (AMI) in 20 patients affected by DOC, before and after the application of a repetitive transcranial magnetic stimulation protocol (rTMS) delivered over the left primary motor area (M1), paired to a transauricular alternating current stimulation.
Our protocol induced potentiating of the electrophysiological markers of AMI and M1 excitability, paired to a clinical improvement, in all of the patients with minimally conscious state (MCS) but in none of those suffering from unresponsive wakefulness syndrome (UWS).
Our protocol could be a promising approach to potentiate the functional connectivity within large-scale audiomotor networks, thus allowing clinicians to differentiate patients affected by MCS from UWS, besides the clinical assessment.
American Psychological Association (APA)
Naro, Antonino& Leo, Antonino& Cannavò, Antonino& Buda, Antonio& Bruno, Rocco& Salviera, Carlo…[et al.]. 2015. Audiomotor Integration in Minimally Conscious State: Proof of Concept!. Neural Plasticity،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075337
Modern Language Association (MLA)
Naro, Antonino…[et al.]. Audiomotor Integration in Minimally Conscious State: Proof of Concept!. Neural Plasticity No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1075337
American Medical Association (AMA)
Naro, Antonino& Leo, Antonino& Cannavò, Antonino& Buda, Antonio& Bruno, Rocco& Salviera, Carlo…[et al.]. Audiomotor Integration in Minimally Conscious State: Proof of Concept!. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075337