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The Role of the Right Dorsolateral Prefrontal Cortex in Phasic Alertness: Evidence from a Contingent Negative Variation and Repetitive Transcranial Magnetic Stimulation Study
Joint Authors
Grippo, A.
Currà, Antonio
Rinalduzzi, Steno
Missori, Paolo
Fattapposta, Francesco
Mannarelli, Daniela
Pauletti, Caterina
Amantini, Aldo
Augugliaro, Vito
Locuratolo, Nicoletta
De Lucia, Maria C.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Phasic alertness represents the ability to increase response readiness to a target following an external warning stimulus.
Specific networks in the frontal and parietal regions appear to be involved in the alert state.
In this study, we examined the role of the right dorsolateral prefrontal cortex (DLPFC) during the attentional processing of a stimulus using a cued double-choice reaction time task.
The evaluation of these processes was conducted by means of Event-Related Potentials (ERPs), in particular by using the Contingent Negative Variation (CNV), and repetitive 1-Hz Transcranial Magnetic Stimulation (rTMS).
Transient virtual inhibition of the right DLPFC induced by real 1-Hz rTMS stimulation led to a significant decrease in total CNV and W1-CNV areas if compared with the basal and post-sham rTMS conditions.
Reaction times (RTs) did not decrease after inhibitory rTMS, but they did improve after sham stimulation.
These results suggest that the right DLPFC plays a crucial role in the genesis and maintenance of the alerting state and learning processes.
American Psychological Association (APA)
Mannarelli, Daniela& Pauletti, Caterina& Grippo, A.& Amantini, Aldo& Augugliaro, Vito& Currà, Antonio…[et al.]. 2015. The Role of the Right Dorsolateral Prefrontal Cortex in Phasic Alertness: Evidence from a Contingent Negative Variation and Repetitive Transcranial Magnetic Stimulation Study. Neural Plasticity،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1075344
Modern Language Association (MLA)
Mannarelli, Daniela…[et al.]. The Role of the Right Dorsolateral Prefrontal Cortex in Phasic Alertness: Evidence from a Contingent Negative Variation and Repetitive Transcranial Magnetic Stimulation Study. Neural Plasticity No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1075344
American Medical Association (AMA)
Mannarelli, Daniela& Pauletti, Caterina& Grippo, A.& Amantini, Aldo& Augugliaro, Vito& Currà, Antonio…[et al.]. The Role of the Right Dorsolateral Prefrontal Cortex in Phasic Alertness: Evidence from a Contingent Negative Variation and Repetitive Transcranial Magnetic Stimulation Study. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1075344
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075344