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The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts
Joint Authors
Leite, Rafaela Torres Portugal
Nogueira, Sarah de Oliveira
Nascimento, João Paulo Rodrigues do
Lima, Laisa Soares de
Nóbrega, Taís Bastos da
Virgínio, Mariana da Silva
Moreno, Lucas Monte da Costa
Sampaio, Bruno Henrique Barbosa
Souza, Fábio Gomes de Matos e
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-13
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Introduction.
Bipolar disorder (BD) implies risk of suicide.
The age at onset (AAO) of BD carries prognostic significance.
Substance abuse may precede the onset of BD and cannabis is the most common illicit drug used.
The main goal of this study is to review the association of cannabis use as a risk factor for early onset of BD and for suicide attempts.
Materials and Methods.
PubMed database was searched for articles using key words “bipolar disorder,” “suicide attempts,” “cannabis,” “marijuana,” “early age at onset,” and “early onset.” Results.
The following percentages in bipolar patients were found: suicide attempts 3.6–42%; suicide attempts and substance use 5–60%; suicide attempts and cannabis use 15–42%.
An early AAO was associated with cannabis misuse.
The mean age of the first manic episode in individuals with and without BD and cannabis use disorder (CUD) was 19.5 and 25.1 years, respectively.
The first depressive episode was at 18.5 and 24.4 years, respectively.
Individuals misusing cannabis showed increased risk of suicide.
Discussion.
Cannabis use is associated with increased risk of suicide attempts and with early AAO.
However, the effect of cannabis at the AAO and suicide attempts is not clear.
American Psychological Association (APA)
Leite, Rafaela Torres Portugal& Nogueira, Sarah de Oliveira& Nascimento, João Paulo Rodrigues do& Lima, Laisa Soares de& Nóbrega, Taís Bastos da& Virgínio, Mariana da Silva…[et al.]. 2015. The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts. Neural Plasticity،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1075346
Modern Language Association (MLA)
Leite, Rafaela Torres Portugal…[et al.]. The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts. Neural Plasticity No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1075346
American Medical Association (AMA)
Leite, Rafaela Torres Portugal& Nogueira, Sarah de Oliveira& Nascimento, João Paulo Rodrigues do& Lima, Laisa Soares de& Nóbrega, Taís Bastos da& Virgínio, Mariana da Silva…[et al.]. The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1075346
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075346